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논문

2023

  • Jeong HC*, Shukla S*, Fok WC, Huynh TN, Batista LFZ, Parker R “USB1 is a miRNA deadenylase that regulates hematopoietic development” Science. 2023 379(6635): 901-7. (Research Highlighted by Nature Review Genetics: https://www.nature.com/articles/s41576-023-00595-9)
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  • Jeong HC*, Go YH*, Shin JG, Kim YJ, Cho MG, Gwon D, Cheong HS, Lee H, Lee JH, Jang CY, Shin HD, Cha HJ “TPX2 amplification-driven aberrant mitosis in culture adapted human embryonic stem cells with gain of 20q11.21” Stem Cell Rev Rep. 2023 doi: 10.1007/s12015-023-10514-4.​
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  • Kim YJ, Go YH, Jeong HC, Kwon EJ, Kim SM, Cheong HS, Kim W, Shin HD, Lee H, Cha HJ “TPX2 prompts mitotic survival via the induction of BCL2L1 through YAP1 protein stabilization in human embryonic stem cells” Exp Mol Med. 2023 55(1): 32-42.

2018 - 2021

  • Vessoni AT, Zhang T, Quinet A, Jeong HC, Munroe M, Wood M, Tedone E, Vindigni A, Shay JW, Greenberg RA, Batista LFZ “Telomere erosion in human pluripotent stem cells leads to ATR-mediated mitotic catastrophe” J Cell Biol. 2021 220(6): e202011014. (Recommended by Faculty Opinions)
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  • Go YH, Kim J, Jeong HC, Kim SM, Kim YJ, Park SJ, Moon SH, Cha HJ “Luteolin induces selective cell death of human pluripotent stem cells” Biomedicines. 2020 8(11): 453.
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  • Munroe M, Niero EL, Fok WC, Vessoni AT, Jeong HC, Brenner KA, Batista LFZ “Telomere dysfunction activates p53 and represses HNF4a expression leading to impaired human hepatocyte development and function” Hepatology. 2020 72(4): 1412-29.
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  • Shukla S*, Jeong HC*, Sturgeon CM, Parker R, Batista LFZ “Chemical inhibition of PAPD5/7 rescues telomerase function and hematopoiesis in dyskeratosis congenita” Blood Adv. 2020 4(12): 2712-22.
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  • Go YH*, Lim C*, Jeong HC*, Kwon OS, Chung S, Lee H, Kim W, Suh, YG, Son WS, Lee MO, Cha HJ, Kim SH “Structure-activity relationship analysis of YM155 for inducing selective cell death of human pluripotent stem cells” Front Chem. 2019 16(7): 298.
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  • Go YH, Lee HJ, Kong HJ, Jeong HC, Lee DY, Hong SK, Sung SH, Kwon OS, Cha HJ “Screening of cytotoxic or cytostatic flavonoids with quantitative Fluorescent Ubiquitination-based Cell Cycle Indicator- based cell cycle assay” R Soc Open Sci. 2018 5(12): 181303.
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  • Cho SJ, Kim KT, Jeong HC, Park JC, Kwon OS, Song YH, Shin JG, Kang S, Kim W, Shin HD, Lee MO, Moon SH, Cha HJ “Selective elimination of culture-adapted human embryonic stem cells with BH3 mimetics” Stem Cell Reports. 2018 11(5): 1244-56.
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2012 - 2017

  • Jeong HC, Park SJ, Choi JJ, Go YH, Hong SK, Kwon OS, Shin JG, Kim RK, Lee MO, Lee SJ, Shin HD, Moon SH, Cha HJ “PRMT8 controls the pluripotency and mesodermal fate of human embryonic stem cells by enhancing the PI3K/AKT/SOX2 axis” Stem Cells. 2017 35(9): 2037-49.
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  • Jeong HC, Cho SJ, Lee MO, Cha HJ “Technical approaches to induce selective cell death of pluripotent stem cells” Cell Mol Life Sci. 2017 74(14): 2601-11. (Invited Review)
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  • Jeong HC and Cha HJ “Helping induced hPSCs clean up their act” Cell Chem Biol. 2017 24(6): 651-2. (Invited Preview)
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  • Kim KT, Jeong HC, Kim CY, Kim EY, Heo SH, Cho SJ, Hong KS, Cha HJ “Intact wound repair activity of human mesenchymal stem cells after YM155 mediated selective ablation of undifferentiated human embryonic stem cells” J Dermatol Sci. 2017 86(2): 123-31. 
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  • Cha Y, Han MJ, Cha HJ, Zoldan J, Burkart A, Jung JH, Jang Y, Kim CH, Jeong HC, Kim BG, Langer R, Kahn CR, Guarente L, Kim KS “Metabolic control of primed human pluripotent stem cell fate and function by the miR-200c-SIRT2 axis” Nat Cell Biol. 2017 19(5): 445-56. (Highlighted by a commissioned News & Views article)
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  • Jeong HC, Choo SS, Kim KT, Hong KS, Moon SH, Cha HJ, Kim TH “Conductive hybrid matrigel layer to enhance electrochemical signals of human embryonic stem cells” Sens Actuator B-Chem. 2017 242: 224- 30. 
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  • Kim SY, Jeong HC, Hong SK, Lee MO, Cho SJ, Cha HJ “Quercetin induced ROS production triggers mitochondrial cell death of human embryonic stem cells” Oncotarget. 2016 8(39): 64964-73.
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  • Yea CH*, Jeong HC*, Moon SH, Lee MO, Kim KJ, Choi JW, Cha HJ “In situ label-free quantification of human pluripotent stem cells with electrochemical potential” Biomaterials. 2016 75: 250-9.
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  • Cho SJ, Kim SY, Jeong HC, Cheong H, Kim D, Park SJ, Choi JJ, Kim H, Chung HM, Moon SH, Cha HJ “Repair of ischemic injury by pluripotent stem cell based therapy without teratoma through selective photosensitivity” Stem Cell Reports. 2015 5(6): 1067-80.
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  • Jeong HC, Gil NY, Lee HS, Cho SJ, Kim K, Chun KH, Cho H, Cha HJ “Timely degradation of Wip1 phosphatase by APC/C activator protein Cdh1 is necessary for normal mitotic progression” J Cell Biochem. 2015 116(8): 1602-12.
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  • Korm S*, Jeong HC*, Kwon OS, Park JR, H Cho, YM Kim, YW Chin, Cha HJ “alpha-Mangostin induces G1 cell cycle arrest in HCT116 cells through p38MAPK-p16INK4a pathway” RSC Adv. 2015 5: 34752-60.
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  • Lee MO, Moon SH, Jeong HC, Yi JY, Lee TH, Shin SH, Oh SJ, Lee MY, Han MJ, Cho YS, Chung HM, Kim KS, Cha HJ “Inhibition of pluripotent stem cell-derived teratoma formation by small molecules” Proc Natl Acad Sci U S A. 2013 110(35): E3281-90. (In This Issue)
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  • Lee JS, Kim WS, Kim JJ, Chin YW, Jeong HC, Choi JS, Min HG, Cha HJ "Identification of anti-melanogenic natural compounds from Galega officinalis and further drug repositioning" J Dermatol Sci. 2012 67(1): 61- 3.
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  • Song SH, Lee MO, Lee JS, Jeong HC, Kim HG, Kim WS, Hur M, Cha HJ "Genetic modification of human adipose-derived stem cells for promoting wound healing" J Dermatol Sci. 2012 66(2): 98-107. (The Editor’s Choice)
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